This presentation will discuss one of the most exciting scientific discoveries of this or any century: The completion and consequences of the Human Genome project. With the publication of the sequence of the Human Genome, the scientific community has been propelled into a new era of post-genomic science. This is both an exciting and challenging advancement. The Human Genome project has forever changed the way that science is approached. The technological advances coupled with the vast amount of information that the Genome project has produced sets the stage for the examination of other areas of biology to be analyzed using a similar "Big Science" approach. Thus, several new fields of molecular and cellular biology have been born, including proteomics, the study of a complete complement of proteins, their interactions and functions within a cell or organism. This presentation will describe how a scientist can use information obtained by the Genome Project to understand how a cell functions. We will discuss how we obtain information from genes to make proteins and how we can use these proteins in the laboratory. We will also discuss career opportunities in science and where the next scientific hot spots are to be found! This is the fourth presentation in this year's Science on Saturday lecture series. The series is co-hosted by LLNL's Science & Technology Education Program and Sigma Xi.